It is well known that the sense of touch is affected early in many types of neuropathies. The exact mechanisms and sequences are less well known and many areas remain to be discovered. VibroSense Dynamic has an explicit strategy to conduct research in close cooperation with research partners. The goal is to build a comprehensive research portfolio based on the company's technology Multi Frequency Vibrometry (MFV).
VibroSense has since its start developed and refined MFV and its strength has been manifested in 28 scientific publications. VibroSense is currently conducting studies in collaboration with research partners, within two main areas: diabetes and chemotherapy of cancer.
Strong decision support for diagnostics
Multi Frequency Vibrometry is a method that provides strong decision support in the diagnosis of peripheral nerve injuries in the hands and feet by examining and quantifying the ability to perceive vibrations.
We collaborate with researchers and research networks, which opens opportunities to discover entirely new knowledge’s that can be used to develop improved treatment models. This brings invaluable knowledge to both parties. The researchers are given the opportunity to publish their discoveries in scientific journals and VibroSense get the sole right to implement new findings in proprietary software algorithms for decision support in diagnostics.
Possibility to analyse multiple parameters
The VibroSense Meter II system is well suited for research in virtually all areas that affect peripheral neuropathy in hands, fingers and feet.
The strength of the system is that it can handle extensive data of vibration thresholds which is stored in a database. This can also be supplemented with other parameters such as weight, length etc. All data can easily be exported for further analysis with different statistical methods, such as multivariate analyses.
Below all currently running diabetes studies are listed:
1. Comparative study of adults with type I diabetes (DMT1)
The purpose of the study is to compare three traditional methods for the diagnosis of diabetes neuropathy. Within the study the Biothesiometer, Neurography and Multi Frequency Vibrometry are compared. The study ends in spring 2019.
Several interesting discoveries have been made in our latest completed diabetes studies:
1. Study of children and adolescents with type I diabetes (DMT1)
A cohort with 72 children and adolescents aged 8–18 years was examined with the VibroSense Meter system to investigate the prevalence of Diabetic Peripheral Neuropathy (DPN) in the hands and feet.
2. Study of adults with diabetes type I (DMT1) with long duration
A cohort with 125 adults was examined for 2 years with the VibroSense Meter system to investigate if there is a correlation between change in HbA1c levels and change of the vibration sensitivity in the soles of the feet.
3. Study of adults with type I diabetes (DMT1)
A cohort with 364 adults was examined in order to evaluate whether Multi Frequency Vibrometry can be used to detect a correlation between diabetic foot ulcers (DFU) and impaired sensitivity in the soles of the feet.
Currently, three oncology studies are conducted. A new study is planned to start after summer 2019
1. Pilot study, colorectal cancer using Oxaliplatin
The study is conducted at Skåne University Hospital in Malmö and the hospital in Kristianstad.
The purpose of the study is to investigate whether Multi Frequency Vibrometry can be used to detect Chemotherapy Induced Neuropathy (CIPN). The long-term goal is to develop individual treatment regimens to reduce the incident of CIPN.
2. Pilot study, colorectal cancer using Oxaliplatin
The study is conducted at Linköping University Hospital. The purpose of the study is to investigate whether Multi Frequency Vibrometry can be used to detect Chemotherapy Induced Neuropathy (CIPN). The long-term goal is to develop individual treatment regimens to reduce the incident of CIPN.
3. Pilot study, multiple myeloma treated with Bortezomib
The study is conducted at the clinic of haematology at Skåne University Hospital in Lund. The purpose of the study is to investigate whether Multi Frequency Vibrometry can detect CIPN.
No additional studies are currently conducted.